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Just something I threw together. Welcome any input.

This is my build I use in 76

Since meat hooks use both one-handed melee and unarmed perks and effects, this is my build for making it work. Some of the int perks are placeholders as I still want a decent int for getting xp until we learn what prestige perks every 50 levels do.

This is my “bring whatever I want to the queen and shoot/beat her in the head” build (hence the +crit mutation). Bloodied and 5/5 Unyielding is plenty OP so this should do plenty of damage as long as you have a decent weapon. This would also be great at testing mods/new gun types since there isn’t any bias to a certain weapon category, although keep in mind that melee gets 75% armor pen, heavy guns can get 45% armor pen in PA, and rifles get 36% armor pen. Also keep in mind th…

Working up an idea for a straight heavy gunner. Idea is to use Furious or Anti-Armor weapons and PA.

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This is a Queen Scratcher template, that will give you a decent example of character that is able to deal extreme damage to bosses with unarmed weapons.
It leaves some points that could be spent either to boost the performance, or smooth the quality-of-life concerns. As it is, full of holes, this will still be at decent, as it contains all mandatory things to ensure high performance.
You want to maximise you strength with all you can, hence you’ll use low HP and Unyielding armor i…

This is a Carpet Bomber template, that will give you a decent example of character that is able to carpet-bomb an area to break all the bones that could be found there.
It leaves some points that could be spent either to boost the performance, or smooth the quality-of-life concerns. As it is, full of holes, this will still be at decent, as it contains all mandatory things to ensure high performance.
It works best when used on high rate of fire, multi-projectile weapons. Beam Splitter Plasma and…

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This is a Staggermaister template, that will give you a decent example of character that is able to carpet-bomb an area to break all the bones that could be found there.
It leaves some points that could be spent either to boost the performance, or smooth the quality-of-life concerns. As it is, full of holes, this will still be at decent, as it contains all mandatory things to ensure high performance.
Shotguns shoot with multiple projectiles. Each projectile can break a bone thanks to En…

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This is a sneaky sniper template, that will lay a solid foundation for optimized sneaky sniper builds.
It leaves some points that could be spent either to boost the performance, or smooth the quality-of-life concerns. As it is, full of holes, this will still be at decent, as it contains all mandatory things to ensure high performance.
Sneakiness is greatly boosted with agility, and sniperness is greatly boosted with luck, hence I’d suggest going the low-HP route, using unyielding …

ARMORS:
5 x unyielding
under armor: Shielded road leathers
Mutations:
Adrenal Reaction
Bird Bones
Carnivore
Eagle Eyes
Grounded
Healing factor
Marsupial
Scaly Skin
Speed Demon

To answer some questions I had with this build before playing it:
Q: Why no Action Boy?
A: You have 30 agility with full Unyielding before any +stats from chems or minor armor effects, plus hopefully at least one piece of armor with AP refresh. You’re good on AP. Plus the SBQ will bug you out at 0 AP anyway.
Q: Why not have maxed out Rifleman perks?
A: Your damage is good enough, trust me. Granted it’d be 6 points for 30% damage so very similar to two more full Bloody Mess cards, bu…

Level 50 56/56 points 180 lbs 297 HP 180 AP
Special Points:
Strength – 2
Perception – 15
Endurance – 3
Charisma – 4
Intelligence – 8
Agility – 12
Luck – 12
Perk cards:
Strength – Strong back (2)
Perception – Rifleman (3), Expert Rifleman (3), Master Rifleman (3), Tank killer (3). Concentrated Fire (3)
Endurance – Rejuvenated (1), Dromedary (2)
Charisma – Lone Wanderer (4)
Intelligence – First aid (3), Weapons…

ARMORS:
4 x unyielding +1 agility
1 x ulyielding + 1 luck
under armor: Shielded road leathers
when you have 30 luck every third shot in vats will be crit
i use rank 4 lifegiver in a bloodied build because there is a health regen glitch when you very low health start sprinting and lifegiver perk will regen your health up to 45 suddenly.
Weapons:
every auto pistol with Bloodied +%50 vats crit 
Mutations:
Adrenal Reaction
Bird Bones
Carnivore
Eagle Eyes
Grounded
Healing factor
Marsupial
Scaly Skin…

What is this build for?
This build is for Bloodied Explosive Heavy Guns. It requires a LOT of resources, for a maximum of damage. You’ll need to farm Lead, Steel and Fusion Cores. And a crap-ton of acid. There’s NO weight reduction perks for the ballistic ammo in this build because each SPECIAL points counts. You’ll need to stay at or below 20% health via radiation.
How to play : Power Armor (Queen)
During the Queen fight, you’ll not use VATS. Your AP will help you survi…

Might need to toy around with this one. Would like to incorporate either unyielding or power armor with Emergency Mod. Just a thought, nothing serious.